Osteoconductive three-dimensional scaffold with cortical & cancellous components

Demineralized bone scaffold with osteoinductive potential, which provides exposure of signaling molecules and bone morphogenetic proteins¹

Bone-derived cells to support osteogenic healing processes

Proprietary, optimized bone microparticulate size range of 100-300 μm²

DMSO-free cryoprotectant with no rinsing and decanting steps required

Average cell viability exceeds 80% post-thaw³

Minimum of 150,000 viable cells per cc of allograft post-thaw³

Convenient handling and preparation time in the OR

Four hour working window for implantation after thaw without loss of cell viability

Product shelf-life is two years from date of processing when stored at -65°C or colder

Reference:

1. Gruskin, E. et.al., Demineralized bone matrix in bone repair: history and use.
Advanced Drug Delivery Reviews, 2012. 64:1063-1077.

2. Malinin, T.I., et. al., Particulate bone allograft incorporation in regeneration of osseous
defects; importance of particle sizes. The Open Orthopeadics Journal, 2007. 1:19-24.

3. Data on file at Vivex Biomedical, Inc.